CORDIS Project
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This project explores the evolution of bacterial immune mechanisms, including surface modification and CRISPR-Cas systems. It combines laboratory experiments and ecological studies to understand how various factors influence the development and effectiveness of these immune strategies in natural environments.
Bacteria have a range of immune mechanisms, but it is unclear why this diverse armamentarium evolved.
The most important immune mechanisms are (1) Surface Modification (SM) (2) Abortive infection (Abi) (3) Restriction Modification (R-M) (4) CRISPR-Cas and (5) prokaryotic Argonaute (pAgo), all of which can occur as stand-alone mechanisms or in combination.
The individual mechanisms differ in key aspects, such as their fitness costs (constitutive versus inducible), specificity (indiscriminate vers…
THE UNIVERSITY OF EXETER
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
New Zealand, Dunedin
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
United Kingdom, Liverpool
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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