CORDIS Project
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This project focuses on enhancing the directed evolution of proteins using innovative microfluidic technology. By utilizing monodisperse oil-in-water microdroplets, it enables high-throughput screening of enzyme variants, making the process more efficient and cost-effective for the biotechnology industry.
Directed evolution of functional proteins has arguably emerged as an approach to protein engineering that can complement or better design-led approaches to protein function.
However, as a random process, enormous numbers of variants have to be screened and selected to have a chance to identify successful catalysts.
This process is costly and cumbersome:
Industrial screening facilities require investment of tens to hundred of millions of dollars.In the context of ERC StG “ChemBioMech” key steps t…
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