CORDIS Project
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This project investigates the mechanisms of spiral cleavage in early embryonic development across various species. It aims to understand how maternal factors influence cell fate specification and the evolution of these processes.
Spiral cleavage is a highly stereotypical early embryonic program, and the ancestral, defining feature to Spiralia, a major phylogenetic clade including almost half of the animal phyla.
Remarkably, spiral-cleaving embryos specify homologous cell fates (e.g. the progenitor cell of posterodorsal structures) conditionally –via cell interactions– or autonomously –via segregation of maternal inputs.
This variation occurs naturally, even between closely related species, and has been related to the pre…
QUEEN MARY UNIVERSITY OF LONDON
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