CORDIS Project
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This research investigates primitive phosphorus-based chemicals that may have predated adenosine triphosphate (ATP) in early life forms. It explores the potential of pyrophosphite to facilitate peptide formation, aiming to understand the chemical evolution leading to ATP-like systems.
Contemporary biochemistry exploits condensed polyphosphates (e.g.: adenosine triphosphate, ATP) to drive metabolic processes.
However, it is unlikely that such molecules emerged a priori from an abiotic environment as their synthesis and use requires the presence of sophisticated & complex protein catalysts.
We propose that more primitive P-based chemicals pre-dated ATP, chemicals which (i) emerged readily from prebiotic environments, (ii) were capable of performing valuable (in the context of a…
UNIVERSITY OF LEEDS
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