CORDIS Project
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This project focuses on understanding the epigenetic changes in prostate cancer before and after hormone therapy. It aims to identify new biomarkers and therapeutic targets by analyzing DNA methylation and Polycomb protein activity in tumor tissues.
Prostate cancer is among the leading tumor types in men in the Western world.
The heterogeneity of prostate cancer provides difficulties in tumor classification and decision-making for therapies.
The establishment of new biomarkers is essential to develop individual treatments and facilitate tumor categorization.
Therapies include hormone deprivation, which initially leads to tumor regression, but is associated with a high rate of recurrence.
Both genetic and epigenetic alterations have been fou…
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