CORDIS Project
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This project develops an in-vivo imaging biomarker to assess the function of multidrug transporters in the brain. It aims to improve the prediction, diagnosis, and treatment of central nervous system diseases by understanding how these transporters affect drug efficacy and the clearance of toxic substances like amyloid…
We aim develop in-vivo imaging biomarker of multidrug transporter function as a generic tool for the prediction, diagnosis, monitoring and prognosis of major CNS diseases, as well as to provide support and guidance for therapeutic interventions.
Multidrug transporters actively transport substrates (including multiple CNS drugs) against concentration gradients across the blood-brain barrier (BBB).
Overactivity of these efflux transporters results in inadequate access of CNS drugs to their targets…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
MEDIZINISCHE UNIVERSITAET WIEN
Austria, Wien
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER
Germany, Hannover
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, MUNCHEN
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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