CORDIS Project
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This project investigates the role of primary cilia in various human disorders, particularly those affecting the kidneys. By studying specific syndromes, it aims to understand ciliary dysfunction and its implications for renal cyst formation, ultimately seeking to identify potential therapeutic agents.
Primary cilia have been recognized on nearly all-mammalian cells.
Emerging data suggest that they act as cellular antennae with diverse motility and sensory functions, detecting a wide variety of signals.
As such, defects in cilia formation or function have profound effects on the development of body pattern and the physiology of multiple organ systems.
Ciliary defects underlie a wide range of human disorders, including the rare and heritable Bardet-Biedl (BBS), Oro-facial-digital type 1 (OFD1)…
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LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Freiburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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