CORDIS Project
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This project investigates the mechanisms of cell lineage during the development of multicellular organisms, focusing on asymmetric cell division in yeast. It aims to identify key properties of cell cycle control and the determinants of cell fate that influence self-renewal and differentiation.
One of the modern challenges of cell biologists is to fully understand the mechanisms underlying cell lineage that takes place during the development of multicellular organisms.
This is of importance in context of adult stem cells that alternate between quiescent and proliferation states, then dividing asymmetrically to give rise to a self-renewal stem cell plus a differentiating cell.
The asymmetric determinants conferring self-renewal properties are still unknown.
Of interest, in yeast Sacchar…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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