CORDIS Project
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This project investigates the role of sulfur-containing compounds in cellular oxidative stress, which is linked to various diseases. It aims to characterize enzymatic activities that form and break carbon-sulfur bonds, potentially leading to new medical and industrial applications.
Oxidative stress causes cancer, cardiovascular, neurodegenerative and infective disease.
Much of cellular oxidative stress is mediated, communicated, mitigated or amplified by a complex system of sulphur containing small metabolites or protein based cysteines.
Characterization of key players and reactions in this network is crucial for preventive and therapeutic interventions.I propose a new perspective on sulphur biochemistry.
The reactivity of sulphur with the oxidative stressors superoxide, p…
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