CORDIS Project
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This project focuses on the role of DNA methylation in regulating gene expression in the pathogenic bacterium Acinetobacter baumannii. By understanding these epigenetic mechanisms, the research aims to identify new targets for treating infections caused by this bacterium.
Gene expression in bacteria is regulated by a multitude of mechanisms to facilitate adaptation to changing environmental conditions and during infection, which is key to their evolutionary success.
To ensure that genes are only expressed in the right place and at the right time, access of transcription factors to promoters that drive gene expression can be controlled by DNA binding proteins and DNA methylation. DNA methylation is a seemingly simple, yet powerful mechanism mediated by methyltrans…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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