CORDIS Project
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This project investigates DNA methylation, a key epigenetic mark, by studying nine proteins that recognize it in human cells. Using advanced genome-wide techniques, it aims to create a comprehensive understanding of how DNA methylation regulates gene expression, which could enhance basic research and have medical appli…
Epigenetics is a new frontier in biology.
It has yielded revolutionary insight into how the genome works, and has profound implication for human health.This project focuses on the best-established epigenetic mark, DNA methylation.
This mark is essential for the embryonic development and adult life of mammals, and acts primarily by regulating gene expression.While the essential functions of DNA methylation are well-known, our knowledge of its effectors is very limited.
Nine mammalian proteins are…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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