CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
EpiTransformers investigates how normal blood stem cells transform into leukemic cells through epigenetic changes. By utilizing advanced profiling technologies and in vivo models, the project aims to uncover the mechanisms behind this transformation and identify potential therapeutic targets for leukemia treatment.
A major gap in knowledge exists relating to the mechanisms via which a normal hematopoietic stem cell attains a fully transformed state via preleukemic intermediates.
It is now accepted that a key player in this transition is epigenetic plasticity.
Identifying the epigenetic mechanisms regulating the transformation of normal to leukemic stem cells will open new avenues for the identification of therapeutics at different stages of disease. A characteristic stem cell-like gene expression pattern i…
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
