CORDIS Project
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EPISTOP is a groundbreaking study investigating the early stages of epilepsy in infants diagnosed with Tuberous Sclerosis Complex. By examining risk factors and biomarkers before seizure onset, the project aims to uncover new therapeutic targets to prevent or modify the development of epilepsy.
Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications.
The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism.
The development of epilepsy (epileptogenesis), extensively studied in animals, is barely studied in humans, as patients usually present AFTER the seizure onset.EPISTOP is the first prospective study of epileptogenesis in huma…
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