CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the epigenetic reprogramming of germ cells during fertilization, focusing on the paternal contribution to the zygotic epigenome. It aims to uncover the mechanisms of sperm chromatin reorganization and the inheritance of epigenetic modifications, with implications for reproductive biology.
During gametogenesis, germ cells undergo profound chromatin reorganisation, condensation and transcriptional shutdown.
Upon fertilization, gamete chromatin is epigenetically reprogrammed, generating a totipotent zygote that can give rise to all cell types of the adult organism.
The maternal factors that reprogram gametes to totipotency are unknown.
The current dogma suggests that the parental epigenetic information must be erased in order to establish totipotency.
In contrast, we have recently d…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
