CORDIS Project
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This project investigates the role of DNA methylation in mammalian reproduction, focusing on how these epigenetic modifications affect gamete quality and offspring development. By studying these processes in mice and humans, the research aims to enhance understanding of fertility and its implications for developmental…
By standing at the crossroads of generations, germ cells ensure species continuity.
At the time of fertilization, the oocyte and spermatozoon carry the genetic material but also non-genetically encoded, epigenetic information.
Gametic epigenetic modifications have immediate effects on gametic production and fertility.
They also have long-term consequences on somatic phenotypes when transmitted to the progeny.
Our team has previously made some important contributions to the emergence of these con…
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