CORDIS Project
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This project investigates the role of a specific protein fragment in Alzheimer's disease, focusing on its effects on gene regulation and the degradation of harmful peptides in the brain. By studying various brain cell models, it aims to identify new therapeutic strategies for neuroprotection.
Alzheimer’s disease (AD) and other dementias affect over 7 million individuals in Europe.
There is, as yet, no treatment to halt or reverse disease progression despite huge investments into research.
The accumulation of the amyloid beta-peptide (Abeta), derived from the amyloid precursor protein (APP) in the brain, is a key factor in the development of AD but the roles of other APP metabolites are poorly understood.
This project will focus on one of these metabolites, its intracellular domain, A…
UNIVERSITY OF LEEDS
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