CORDIS Project
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EpiPrevent investigates the role of inflammation in post-traumatic epilepsy by targeting the P2X7 receptor. The project aims to assess the potential of P2X7 receptor antagonism for preventing epilepsy development and improving patient stratification for treatment.
Post-traumatic epilepsy (PTE) is one of the most common, devastating complications following traumatic brain injury (TBI), and is particularly prone to drug-refractoriness.
Critically, current anti-seizure medication remains ineffective in over 30% of patients, with no impact on disease progression and frequent adverse side effects.
Increasing evidence suggests inflammation as one of the main contributors to the development of PTE. ATP, released during pathological processes in the brain, functi…
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Spain, San Sebastian
Type: Research institute
Activity type: Research Organisations
SME: No
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