CORDIS Project
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This project investigates how oral epithelial cells develop memory to manage Candida albicans infections and maintain a healthy microbiota. By exploring the interactions between these cells and the fungus, the research aims to uncover mechanisms that enhance immune responses and promote balance in oral health.
In this research project I seek to discover the mechanisms underlying oral epithelial cell (OEC) memory and its importance to control Candida albicans infections and commensalism. C. albicans is part of the healthy microbiota, but it is also the most clinically relevant fungus.
Fine tuning of mucosal immunity enables homeostasis and regulates commensal-to-pathogen transition of C. albicans.
Innate immune cells, such as macrophages, can develop long-term responses during systemic infections, enab…
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