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EPIGENHEART focuses on understanding congenital heart diseases by studying the genetic and epigenetic factors involved in heart development. It explores the role of retinoic acid signaling in heart formation, aiming to uncover mechanisms that lead to heart defects.
EPIGENHEART proposes a unique and competitive training for heart development research centred on congenital heart diseases (CHD), a leading cause of death in Europe .
Defects in the pathways involved in myocardial lineages at the venous pole of the heart are found to be the origin of CHD and atrial arrhythmias.
Epigenetic gene regulation has influence in maintenance of cellular identity, differentiation, and is deregulated in many diseases.
The involvement of epigenetic dysregulation in CHD is p…
UNIVERSITE D'AIX MARSEILLE
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