CORDIS Project
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This project focuses on developing advanced methods to detect epigenetic markers in circulating tumor DNA from blood samples. By analyzing DNA methylation profiles and associated transcripts, it aims to create more sensitive and informative non-invasive diagnostic tests for cancer, improving patient management and moni…
The detection of circulating tumor DNA allows to non-invasively retrieve tumor molecular profiles and follow disease evolution.
These approaches promise optimal and individualized management of patients with cancer.
However, despite remarkable progress, several technological obstacles still limit liquid biopsy widespread application.
Indeed, detecting small fractions of tumor DNA released when the tumor burden is reduced remains a challenge.
Samples collected at early stages or during treatment…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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