CORDIS Project
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This project investigates how epigenetic modifications influence stem cell fate in the cnidarian Hydractinia echinata. By mapping DNA methylation and histone modifications, it aims to understand the role of these modifications in cell differentiation and their implications for regenerative medicine and cancer research.
Epigenetics is a new and exciting area in biomedical sciences.
It studies mitotically heritable chemical modifications of chromatin that are not associated with changes in the DNA sequence.
Epigenetic modifications (EMs) affect the expression of genes, and therefore the phenotype of cells.
Current views suggest that epigenetics reinforces cell fate stability.
Indeed, EMs are essential for normal development and tissue homeostasis, and improper regulation may result in diseases like cancer.
Despi…
UNIVERSITY OF GALWAY
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