CORDIS Project
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The project focuses on understanding how gene regulation and epigenetic factors influence the development of distinct neuronal subtypes in the mammalian cortex. By employing advanced techniques like single-cell RNA sequencing and chromatin analysis, it aims to map the regulatory landscape and elucidate the mechanisms o…
The mammalian cortex is the most complex region of the brain responsible for higher cognitive functions.
Abnormal cortical development often translates into prominent neuropsychiatric diseases, which affect different neuronal subtypes with unique molecular and morphological features.
Increasing evidence suggests that epigenetic regulation is essential for cortical development but how multiple regulatory layers are coordinated to specify distinct neuronal lineages in vivo remains unclear.My team…
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
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