CORDIS Project
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This project investigates how adiponectin, a molecule released by epicardial adipose tissue, affects heart function and redox state. It aims to understand the communication between heart tissue and adipose tissue, potentially revealing new insights into heart disease mechanisms.
Recent evidence suggests that adipose tissue (AT) affects vascular and cardiac function, through the release of bioactive molecules called adipokines.
Adiponectin is an adipokine with potent antiatherogenic effects in experimental studies, while in clinical studies adiponectin is paradoxically an independent predictor of poor clinical outcome of heart failure patients.
Up to now the role of adiponectin released by epicardial AT and the role of epicardial fat pad in total in myocardium biology re…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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