CORDIS Project
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This project investigates how enzymes function as catalysts in non-aqueous organic solvents, aiming to enhance their activity through a better understanding of their interactions with solvents and additives. By utilizing modeling and simulations, it seeks to optimize enzyme performance for various synthetic chemistry a…
Enzymes are remarkably efficient catalysts and their recent use in non-aqueous organic solvents is opening a tremendous range of applications in synthetic chemistry: since, surprisingly, most enzymes do not denature in these non-natural
environments, new reactions involving e.g. water-insoluble reagents can be catalyzed, while unwanted degradation side reactions are suppressed.However, a key challenge for these applications is to overcome the greatly reduced catalytic
activity compared to aqueou…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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