CORDIS Project
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This project develops a hybrid methodology that combines computational biophysics and experimental structural biology to analyze the dynamic structures of large proteins. By utilizing advanced image processing techniques, it aims to create detailed energy landscapes of ionotropic glutamate receptors, enhancing our unde…
Proteins are dynamic entities that undergo many structural transitions and fluctuations, which are essential to their biological functions.
We, therefore, need continuous descriptions of protein conformational space in the form of energy landscapes in order to properly understand their mechanisms of action.
This is now becoming possible through the use of hybrid methods, which combine computational biophysics with experimental structural biology and overcome the limitations of either approach al…
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
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