CORDIS Project
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This project focuses on developing new enantioselective addition reactions using isocyanoacetate under cooperative catalysis. By designing innovative catalytic systems, it aims to enhance the efficiency of asymmetric bond formation, particularly in biologically relevant compounds.
Enantioselective Isocyanoacetate Addition Reactions under Cooperative Base and Lewis Acid Catalysis.
Enantiomerically pure substances with the capacity to simultaneously activate two reagents towards one another, offer numerous opportunities for the discovery of powerful, asymmetric bond forming reactions.
When a compound possesses a combination of Brønsted (or Lewis) basic and Lewis acidic sites, has a well-defined chiral pocket constructed around a fairly rigid skeleton and appropriate distanc…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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