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The ENGRAB project aims to enhance antibody engineering by developing a bioinformatics platform to analyze antibody responses. It focuses on creating bispecific antibodies to improve therapeutic efficacy against infectious diseases.
Antibodies represent a powerful defense mechanism due to their capacity to link specific antigen recognition with effector functions and are currently developed as drugs for prophylaxis and therapy of infectious diseases.
The generation of antibody diversity represents a remarkable example of protein engineering that is coupled to a stringent mechanism of clonal selection.
In the ENGRAB project we propose first to develop an integrated bioinformatics platform to unravel the clonal dynamics of an…
FONDAZIONE ISTITUTO NAZIONALE DI GENETICA MOLECOLARE INGM
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