CORDIS Project
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This project focuses on enhancing the generation of kidney organoids from human pluripotent stem cells by applying controlled physical and metabolic cues. It aims to improve the differentiation potential and functionality of these organoids, which could lead to better models for studying kidney development and diseases…
Research with human pluripotent stem cells (hPSCs) has led to the development of miniorgan-like structures in culture, so called organoids.
Generally, organoids are generated exploiting cell-autonomous responses of hPSCs with minimal control over the external inputs supplied to the system.
The unrestrained nature of these approaches explains, in part, key shortcomings of the organoid technology, such as limited capacity to recreate all cell types within an organ, maturation and function.Data fro…
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
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