CORDIS Project
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The ENGAGE project focuses on enhancing bone regeneration by developing new proteins that specifically bind to Bone Morphogenetic Proteins (BMPs). By utilizing computational design and biomimetic strategies, the project aims to create hydrogel biomaterials that can effectively sequester growth factors from the extracel…
The successful regeneration of bone tissue to replace areas of bone loss in large defects remains a significant clinical challenge.
Efforts have concentrated in the design of biomaterials using biomimetic strategies based on installing bioactivity at their surface using proteins from the extracellular matrix (ECM).
Some of these ECM proteins contain domains capable of binding growth factors (GFs).
This is the case of the Heparin Binding II (HBII) domain of fibronectin, which has the capacity to…
UNIVERSITAT POLITECNICA DE CATALUNYA
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United States, Seattle Wa
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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