CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project explores how ancient viral sequences in our genome, specifically endogenous retroelements like LINE1, influence immune system regulation. By studying their transcription in response to stressors, the research aims to uncover their potential role in immunity and disease, using mouse models and advanced sequ…
Almost half of our genome is occupied by ancient viral sequences that can be mobilized under certain conditions and either jump or copy themselves from one location to another. A group of these mobile genetic elements is called endogenous retroelements.
Mobilization of retroelements like LINE1 has been shown to cause cancer via insertional mutagenesis.
In recent years LINE1 activation has also been associated with the development of inflammatory diseases and inflammation-driven ageing.
This mean…
UNIVERSITATSKLINIKUM BONN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
