CORDIS Project
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This project investigates the ESCRT machinery's role in membrane fission during cell division. By using advanced imaging techniques, it aims to uncover how ESCRT proteins function and are regulated, contributing to our understanding of various cellular processes.
The ESCRT machinery is a multi-protein complex involved in membrane constriction and fission in a variety of processes in cells including receptor degradation, viral budding and cytokinesis.
The mechanism by which ESCRT proteins drive membrane fission in cells is still largely unknown.
Using super resolution fluorescence microscopy and quantitative live cells imaging I have recently mapped the spatiotemporal organization of ESCRTs in cytokinesis.
The results identified a sequential recruitment o…
BEN-GURION UNIVERSITY OF THE NEGEV
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