CORDIS Project
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EMPATIC aims to develop an innovative platform for creating functional human cardiac tissues in the lab. By integrating biochemical and biophysical stimuli with bioelectronic components, it enables better maturation of heart cells and non-invasive monitoring of their electrical properties, addressing challenges in drug…
Cardiovascular diseases are the major cause of mortality worldwide, making the demand for new therapies an urgent need.
Additionally, unexpected cardiac adverse effects are the leading causes of discontinuation of clinical trials and withdrawal of drugs from the market.
Such issues could be addressed by relevant in vitro human cardiac tissue models reproducing in vivo-like pharmacological response.
However, most in vitro cardiac tissue models developed so far have been limited by complex design…
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