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EMERALD focuses on the automated diversification of indole compounds for drug discovery. By integrating multicomponent reactions and enzymatic processes, it aims to create a sustainable pipeline for generating novel drug candidates with improved efficiency and reduced environmental impact.
Indoles are among the most widely encountered scaffolds in medicines and natural products, yet general strategies for their systematic diversification remain limited.
Through EMERALD (Enzyme-integrated high-throughput Multicomponent synthesis for Echo enabled Rapid molecule generation and Assay in Lead Discovery), I will unites three complementary techniques into the first miniaturized, automated pipeline for late-stage indole diversification at nanoliter scale (i) multicomponent reactions for e…
UNIVERZITA PALACKEHO V OLOMOUCI
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United Kingdom, St Andrews
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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