CORDIS Project
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This project investigates cyclotides, stable plant-derived mini-proteins, to understand their interactions with biological membranes. It aims to elucidate the structural features that influence their bioactivity, which could inform future drug design.
The utility of conventional peptides in pharmaceutical and biotechnological applications is limited by their poor stability and bioavailability.
Cyclotides are plant derived mini-proteins with unique structural properties that make them exceptionally stable and have a range of exciting applications in drug design and agriculture.
Beside the variety of intrinsic activities, there are still many unanswered questions regarding the mechanism involved in cyclotides activity.
Understanding how they ex…
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
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