CORDIS Project
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This project investigates how cancer cells survive in the bone marrow despite treatment, focusing on the immune system's failure to eliminate these cells. By studying immune and stroma cells, the research aims to develop new strategies to enhance immune responses against cancer in this critical environment.
The bone marrow (BM) represents the prime location in which cancer cells survive aggressive treatments.
This poses a major health challenge because the mortality rate of patients with curable cancer doubles if tumor cells persist in the BM.
One unresolved question is why the immune system fails to eradicate cancer cells from this microenvironment even though it represents a lymphatic organ.
Surprisingly, despite the ongoing revolution in immune oncology, the regulation and potential therapeutic…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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Germany, Hamburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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