CORDIS Project
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This project aims to enhance the fluorination and trifluoromethylation of functionalized piperidines using an electrochemical flow microreactor. By improving reaction yield, safety, and sustainability, it addresses key challenges in the pharmaceutical industry related to fluorination chemistry.
Despite the prevalence of fluorination reactions of organic compounds in the pharmaceutical industry, these reactions still encounter several problems such as low selectivity, yield, high demand on safety operational process and low sustainability.
Introduction of fluorine into drug molecules increases the drug’s lipophilicity, improves its stability and pharmacokinetic properties.
Thus, the fluorination chemistry is of great importance in a pharmaceutical industry.
This project is focusing on…
UNIVERSITEIT GENT
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