CORDIS Project
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This project investigates how exposure to endocrine disrupting chemicals affects ovarian signaling pathways and reproductive function in mammals. By analyzing ovarian cells exposed to estrogenic chemicals, the research aims to identify molecular mechanisms that could link these chemicals to reproductive diseases.
In adult mammals, ovarian function is characterized by regular cyclic changes, which are critical for the egg development, sex steroid hormones production and fertility.
These processes depend on the tight regulation of the activity of different ovarian signaling cascades that if altered during critical periods of development can lead to adverse effects on reproductive function.
Initial investigations reveal that ovarian development and functions are sensitive to exposure to endocrine disrupting…
University of Novi Sad Faculty of Sciences
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