CORDIS Project
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This project seeks to develop methods for selective oxidation of carbon-hydrogen bonds in organic molecules. By utilizing innovative catalysts and solvents, it aims to enable efficient and enantioselective reactions that could significantly advance synthetic organic chemistry.
Chemo- and enantioselective oxidation of aliphatic C-H bonds is a cornerstone reaction in metabolism.
The ubiquitous presence of multiple and diverse C-H bonds in organic molecules is used by oxidative enzymes to deliver functionality and chirality to metabolite precursors, rapidly creating product diversity.
Despite its huge potential in organic synthesis, non-enzymatic enantioselective C-H oxidation of aliphatic sites remains inaccessible and has never been incorporated in synthesis.
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