CORDIS Project
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This project focuses on understanding the inheritance of epigenetic marks during DNA replication and cell division. It aims to elucidate the mechanisms that maintain heterochromatin stability at centromeres, crucial for proper chromosome segregation.
Studies concerning the mechanism of DNA replication have advanced our understanding of genetic transmission through multiple cell cycles.
Recent work has shed light on possible means to ensure the stable transmission of information beyond just DNA and the concept of epigenetic inheritance has emerged.
Considering chromatin-based information, key candidates have arisen as epigenetic marks including DNA and histone modifications, histone variants, non-histone chromatin proteins, nuclear RNA as wel…
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