CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates how diabetes causes arterial stiffening, which can lead to heart failure. It aims to develop a computer modeling framework to analyze the dynamic mechanical properties of arteries affected by diabetes, enhancing understanding of arterial health and potential treatment strategies.
Accelerated arterial stiffening, an important complication in diabetes, increases cardiac workload eventually leading to heart failure.
The arterial wall —consisting of elastin, collagen, smooth muscle, and glycosaminoglycans— may stiffen in diabetes due to 1) advanced glycation end-product (AGE)-induced collagen cross-linking, 2) calcification, or 3) changed glycosaminoglycan composition.
The exact mechanical stiffening effects of these processes are unknown.
Current preclinical, state-of-the-a…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
United States, New Haven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
