CORDIS Project
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This study aims to understand how mechanical factors influence the health of articular cartilage and the production of structural molecules by chondrocytes. By analyzing cartilage properties under various loading conditions, the research seeks to identify factors that help maintain cartilage integrity.
The key goals of this study are to better understand the properties that prevent articular cartilage from sustaining mechanical damage, and to determine which mechanical factors encourage cultured chondrocytes to produce structural
macromolecules that enable cartilage to withstand mechanical loading.These key goals will be achieved by:(i) determining the storage and loss moduli for cartilage from lower limb joints, using cyclic loading test conditions;(ii) determining
their relationship to struc…
THE UNIVERSITY OF BIRMINGHAM
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