CORDIS Project
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This project explores the role of dUTPases as signaling molecules in cellular processes. By investigating their function in regulating genetic elements, it aims to uncover new mechanisms of cellular signaling and their potential implications in health.
dUTPases (DUTs) are enzymes that regulate cellular dUTP levels to prevent the misincorporation of uracil into DNA.
Recently however, DUTs have been involved in the control of relevant cellular processes.
How these regulatory functions are controlled remains unsolved.
The recent elucidation of the mechanistic role of DUTs in the transfer of staphylococcal pathogenicity islands (SaPIs) by our group has revealed an entirely novel and surprising strategy involving DUTs in signalling.
Namely, we have…
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United Kingdom, Glasgow
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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