CORDIS Project
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This project investigates the interactions between cancer cells and stromal cells within the tumor microenvironment to develop new cancer therapies. By using a novel method called Dual Ribosome Profiling, it aims to reveal the molecular mechanisms that drive tumor growth and resistance.
Cancers develop in very heterogeneous tissue environments.
They depend on the tumor microenvironment (TME) for sustained growth, metastasis, and therapy resistance.
Stromal cells are genetically stable and they have less likelihood to develop resistance than cancer cells.
Therefore, targeting the TME represents an attractive approach for treating cancer.
In order to develop new therapeutic strategies to reprogram the TME and inhibit tumor growth and resistance, it is essential to understand in d…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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