CORDIS Project
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This project explores the molecular mechanisms of desiccation tolerance in organisms that survive extreme dryness. It aims to engineer mammalian cells to withstand dehydration, with potential applications in biotechnology, agriculture, and tissue engineering.
Certain plants, animals and micro-organisms are able to dry out completely and yet remain viable, a phenomenon known as anhydrobiosis ( life without water ), or desiccation tolerance.
This proposal addresses the molecular mechanisms responsible for desiccation tolerance and aims to confer these mechanisms on desiccation-sensitive mammalian cells, establishing a new field in biotechnology: a form of synthetic biology we have called anhydrobiotic engineering.
One feature of anhydrobiotic organism…
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