CORDIS Project
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This project aims to improve drug development by correlating chemogenomic binding parameters with protein target properties. It focuses on understanding the kinetics and thermodynamics of drug interactions to facilitate more efficient drug optimization processes, especially for neglected diseases.
Once a new drug target is discovered, screening techniques are applied to detect prospective hits.
However, which hit should be taken to the next level of development?
This decision is most crucial as it entails huge financial commitments of the subsequent drug optimization.
In consequence drugs are only developed against diseases that promise short-term profit.
Chemogenomic profiling allows to compile parameters characterizing binding of drug candidates that achieve optimal interference with pr…
PHILIPPS UNIVERSITAET MARBURG
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