CORDIS Project
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This project focuses on developing small molecule probes to identify genomic targets of DNA damaging agents used in cancer treatment. By employing innovative techniques, it aims to create a comprehensive map of drug interactions that could enhance understanding of their mechanisms and improve personalized medicine.
This proposal is centred on the development of small molecule probes derived from DNA damaging agents to identify their genomic targets using a novel unbiased approach.
Although, several genotoxic drugs have been used for decades to treat cancers, the exact mechanisms by which they operate are not fully understood.
It is established that these compounds interfere with the processes of transcription and replication, thereby promoting genomic instability and cell death.
However, there is as yet no…
INSTITUT CURIE
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