CORDIS Project
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This project investigates how localized forces within individual cells in Drosophila wings contribute to tissue remodeling and movement. By integrating genetic manipulation and advanced imaging techniques, it aims to understand the role of specific proteins in these processes and develop a novel method for applying for…
My objective is to understand how localized cortical actin/myosin contractility in individual cells within the Drosophila wing hinge and wing blade combine to generate the epithelial remodelling and convergence-extension movements that occur throughout the tissue.
In particular, I will examine the role of the planar cell polarity proteins in generating and/or responding to these forces and test the hypothesis that convergence-extension movements are driven by external stretching forces caused by…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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