CORDIS Project
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This project investigates how certain parasites interact with the midgut of insects, specifically focusing on Drosophila melanogaster as a model. By studying the immune responses and gut microbiota interactions, the research aims to enhance understanding of parasite transmission mechanisms in tsetse flies and sand flie…
For the vast majority of vector borne parasites the ability to overcome the insect midgut defences is central to transmission.
However, for many such diseases we know virtually nothing about the molecular mechanisms involved.
For vectors such as tsetse flies and sand flies the prospects for rapidly improving our understanding of key interactions occurring in the midgut when challenged by parasites is bleak.
This is because the ‘tool box’ required untangling the interactions is very unlikely to…
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