CORDIS Project
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This project develops a high-throughput droplet-based technique for single-cell sequencing of small RNAs and messenger RNAs. It aims to enhance understanding of the regulatory roles of microRNAs in cell fate decisions during blood cell development, addressing gaps in knowledge about non-coding RNA functions in individu…
Droplet-based single-cell RNA-sequencing (scRNA-seq) technologies have penetrated almost all branches of life sciences and have significantly advanced our understanding of cellular processes and organism development.
However, despite their astonishing impact, most of the scRNA-seq technologies reported to date rely on poly(A) tail capture and thus are mainly restricted to the protein-coding RNAs, while neglecting a substantial proportion of the transcriptome, including small non-coding RNAs.
As…
VILNIAUS UNIVERSITETAS
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