CORDIS Project
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This project focuses on creating a diverse library of small molecules to target difficult biological areas, particularly in cancer and infectious diseases. By utilizing advanced synthetic chemistry techniques, it aims to enhance drug discovery processes through innovative molecular design and computational assessments.
There is an undoubted need of new small molecule libraries with high levels of scaffold diversity in order to address challenging ‘undruggable’ biological targets which have proven largely intractable to small molecule modulation using traditional compound libraries.
The efficient de novo generation of such collections presents a formidable challenge to the synthetic chemist; over the course of the last decade diversity-oriented synthesis has established itself as a powerful tool in this regard.…
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